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Apoptosis Activator 2

CAS No. 79183-19-0

Apoptosis Activator 2 ( —— )

Catalog No. M15971 CAS No. 79183-19-0

An apoptosis activator that strongly induces caspase-3 activation, PARP cleavage, and DNA fragmentation.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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5MG	31	In Stock
10MG	49	In Stock
25MG	101	In Stock
50MG	144	In Stock
100MG	259	In Stock
200MG	424	In Stock
500MG	Get Quote	In Stock
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Biological Information

Product Name

Apoptosis Activator 2
Note

Research use only, not for human use.
Brief Description

An apoptosis activator that strongly induces caspase-3 activation, PARP cleavage, and DNA fragmentation.
Description

An apoptosis activator that strongly induces caspase-3 activation, PARP cleavage, and DNA fragmentation; leads to the destruction of cells (Apaf-1 dependent) with IC50 of 4 uM; exert cytostatic and cytotoxic effects on a variety of cancer cell lines while having little or no activity against the normal cell lines tested.
Synonyms

——
Pathway

Apoptosis
Target

Apoptosis
Recptor

Caspase-3
Research Area

Cancer
Indication

——

Chemical Information

CAS Number

79183-19-0
Formula Weight

306.14
Molecular Formula

C15H9Cl2NO2
Purity

>98% (HPLC)
Solubility

DMSO: ≥ 46 mg/mL
SMILES

O=C1N(CC2=CC=C(Cl)C(Cl)=C2)C3=C(C=CC=C3)C1=O
Chemical Name

1H-Indole-2,3-dione, 1-[(3,4-dichlorophenyl)methyl]-

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Nguyen JT, et al. Proc Natl Acad Sci U S A. 2003 Jun 24;100(13):7533-8.
2. Farivar TN, et al. N Am J Med Sci. 2012 Nov;4(11):582-5.

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